Novak Djokovic’s 2026 US Open campaign ended in one of the most surprising Grand Slam results of his career.
The fourth-seeded Serbian, a four-time US Open champion and 24-time Grand Slam winner, was beaten by Argentina’s Mariano Navone in a dramatic five-set first-round battle at Arthur Ashe Stadium. Navone won 7-6(5), 5-7, 4-6, 6-2, 6-1 to eliminate Djokovic from the tournament and end his pursuit of a record 25th Grand Slam singles title.
The result was particularly significant because Djokovic had built one of the strongest first-round records in Grand Slam history. His defeat also came after a match in which the 39-year-old struggled physically, including vomiting and dealing with cramping, back pain and shoulder problems.
Here are five important facts that explain why Djokovic’s first-round US Open exit is such a remarkable result.
1. Djokovic Lost in the First Round of a Grand Slam for the First Time Since 2006
The biggest statistic surrounding Djokovic’s defeat is his extraordinary consistency in Grand Slam opening rounds.
Before facing Navone in New York, Djokovic had not lost his opening match at a major since the 2006 Australian Open. His only other first-round defeat at a Grand Slam came at the 2005 Australian Open.
That means the 2026 US Open loss ended a streak that had lasted roughly two decades.
Djokovic had entered the tournament with an 80-2 record in Grand Slam first-round matches after defeating Giovanni Mpetshi Perricard in the opening round of the 2026 French Open. That victory extended a remarkable record that had appeared almost untouchable.
His loss to Navone therefore was not simply an early defeat. It was an extremely rare event in Djokovic’s Grand Slam career.
For a player who has spent much of his career progressing deep into major tournaments, losing before the second round represents a dramatic change from the standard Djokovic fans have become accustomed to.
2. Mariano Navone Had Never Won a Five-Set Match Before Facing Djokovic
The contrast between the two players’ five-set records made the result even more surprising.
Djokovic entered the match with a 42-12 career record in five-set matches. He had repeatedly demonstrated his ability to survive physically and mentally demanding Grand Slam battles.
Navone, meanwhile, had never won a five-set match before Sunday.
The Argentine entered the match with an 0-4 record in five-set encounters. One of those defeats came earlier in 2026, when he lost a final-set tie-break to Jakub Mensik at Roland Garros.
Yet Navone managed to stay composed as the match moved into its deciding stages.
After Djokovic won the third set and appeared to have regained control, Navone responded strongly in the fourth. He then dominated the fifth set 6-1 to complete the biggest victory of his career.
That turnaround is one of the defining aspects of the match.
3. Djokovic Was Fighting Serious Physical Problems During the Match
The result cannot be discussed without addressing Djokovic’s physical condition.
During the match, Djokovic struggled to move freely and appeared increasingly uncomfortable as the contest progressed. ATP Tour reported that he vomited multiple times and experienced significant physical difficulties.
After the match, Djokovic explained that he was dealing with vomiting, cramping, pain and problems involving his back and shoulder. He also acknowledged that he had considered retiring from the match because of his physical condition.
Despite those problems, Djokovic continued competing.
In fact, he led Navone by two sets to one and had a break advantage in the fourth set. At that stage, it appeared that Djokovic might once again find a way through an extremely difficult match.
Instead, Navone fought back.
The Argentine won the fourth set 6-2 before taking control of the deciding set. Djokovic was unable to recover physically, and Navone closed out the match 6-1.
Djokovic later described the experience as an extremely difficult one physically, while also giving credit to Navone for taking advantage of his opportunity.
4. The Upset Was Even More Surprising Because Navone Has Struggled on Hard Courts
Navone’s victory was particularly unexpected when his previous hard-court record is considered.
The Argentine has traditionally been more comfortable on clay and had struggled to produce the same level of results on hard courts.
According to ATP Tour, Navone arrived in New York with a 12-29 career record at tour level on hard courts, giving him a winning percentage of just 29.3 percent. He was also 4-8 on the surface during the 2026 season before facing Djokovic.
The contrast with Djokovic was enormous.
Djokovic entered the match with a 741-139 tour-level record on hard courts, an 84.2 percent winning rate.
Those numbers illustrate why Djokovic was expected to be the clear favourite.
However, tennis is ultimately decided on the court. Navone produced the performance required when the opportunity arrived, while Djokovic’s physical condition prevented him from maintaining his usual level over five sets.
The upset demonstrates why pre-match statistics can only tell part of the story.
5. Djokovic Had Far More Grand Slam Experience Than Navone
Another remarkable aspect of the match was the enormous experience gap between the two players.
Djokovic arrived in New York as one of the most accomplished players in tennis history.
He had already won 24 Grand Slam singles titles and four US Open championships. His US Open record before the 2026 tournament stood at 95-15, and he had won the title in New York in 2011, 2014, 2018 and 2023.
Navone’s Grand Slam experience was comparatively limited.
Before the Djokovic match, he had a 6-10 record at major tournaments and a 57-67 tour-level record.
The difference was therefore enormous.
Djokovic had played hundreds of high-pressure matches at the biggest tournaments in tennis. Navone was facing one of the greatest players in the history of the sport on Arthur Ashe Stadium.
Yet Navone did not allow the occasion to overwhelm him.
His ability to stay in the contest after dropping the second and third sets ultimately gave him the chance to exploit Djokovic’s physical decline.
How the Match Unfolded
The five-set scoreline tells the story of a match that changed direction several times.
First Set: Navone Takes the Lead
Navone won the opening set 7-6(5), putting Djokovic under immediate pressure.
The Argentine had already achieved something significant by taking a set from a player with Djokovic’s experience, but the match was far from over.
Second Set: Djokovic Responds
Djokovic showed his trademark resilience in the second set.
He won it 7-5 to level the match and began to look more comfortable.
Third Set: Djokovic Moves Ahead
The Serbian then took the third set 6-4.
At this stage, Djokovic had turned the match around and appeared to have positioned himself for another Grand Slam comeback.
But the physical demands of the contest were becoming increasingly difficult for him.
Fourth Set: Navone Changes the Match
Navone responded decisively.
He won the fourth set 6-2, forcing a deciding set against a player who had historically been one of the strongest five-set competitors in tennis.
Djokovic’s physical struggles became increasingly visible, and his ability to move and serve at his normal level was affected.
Fifth Set: Navone Completes the Upset
Navone dominated the deciding set 6-1.
With Djokovic unable to recover physically, the Argentine took advantage and secured the biggest win of his career.
The final score:
Mariano Navone def. Novak Djokovic 7-6(5), 5-7, 4-6, 6-2, 6-1.
The match lasted approximately four hours and 36 minutes, making it a physically demanding battle from beginning to end.
What This Loss Means for Novak Djokovic
Djokovic’s first-round exit raises understandable questions about his physical condition and his ability to continue competing at the highest level.
However, it would be premature to treat one defeat as definitive evidence that his career is coming to an end.
Before the US Open, Djokovic had still shown that he could compete deep into major tournaments.
He reached the Australian Open final earlier in 2026, advanced to the third round at Roland Garros and reached the Wimbledon semi-finals.
Those results demonstrate that Djokovic remained capable of producing strong Grand Slam performances at age 39.
At the same time, his recent physical difficulties cannot be ignored.
He had already suffered a physically difficult defeat to Thiago Agustin Tirante at the Cincinnati Open shortly before arriving in New York. Tirante defeated Djokovic 2-6, 6-4, 6-4 in Cincinnati, with Djokovic struggling physically during the match.
The US Open defeat therefore adds another major warning sign regarding Djokovic’s physical condition.
What This Victory Means for Mariano Navone
For Navone, the victory represents a defining moment in his career.
Defeating a 24-time Grand Slam champion at the US Open is the kind of result that can transform a player’s profile overnight.
The circumstances make the achievement even more memorable.
Navone entered the match without a five-set victory, had a relatively modest hard-court record and was facing one of the most experienced players in tennis history.
Instead of allowing the occasion to overwhelm him, he stayed competitive for more than four hours and took control when Djokovic’s physical condition deteriorated.
The win will undoubtedly rank among the most important victories of Navone’s career.
Djokovic’s US Open Record Makes the Defeat Even More Historic
Djokovic has enjoyed an extraordinary relationship with the US Open.
Before the 2026 tournament, he had won 95 matches in New York and lost only 15. He was also a four-time champion, with his most recent title coming in 2023.
In 2025, Djokovic reached the semi-finals before losing to eventual champion Carlos Alcaraz. He returned to New York in 2026 hoping to challenge for another title and potentially move from 24 Grand Slam championships to a record 25.
Instead, his campaign ended after just one match.
That makes Navone’s victory one of the most significant upsets of the 2026 US Open.
Why Djokovic’s Defeat Was So Unexpected
Several factors combined to make this upset extraordinary:
- Djokovic was the No. 4 seed.
- He had won four US Open titles.
- He had 24 Grand Slam singles titles.
- He had a 95-15 record at the US Open before this tournament.
- He had not lost a Grand Slam first-round match since 2006.
- He entered with a 42-12 record in five-set matches.
- Navone had never previously won a five-set match.
- Navone had a losing career record on hard courts.
- Djokovic had a dominant career record on the surface.
- Djokovic was chasing a record 25th Grand Slam title.
Yet none of those advantages could prevent Navone from producing the biggest result of his career.
Djokovic’s Emotional Reaction After the Match
The defeat was clearly difficult for Djokovic.
After the match, he spoke openly about his physical problems and acknowledged how difficult it had been to compete. He said he had considered retiring but continued because he wanted to finish the contest.
The Arthur Ashe Stadium crowd also played an important role late in the match.
When Djokovic was struggling in the deciding set, spectators attempted to encourage the 39-year-old champion. Djokovic became emotional while acknowledging the support he received from the New York crowd.
Despite his disappointment, he also praised Navone and recognized the Argentine’s achievement.
That reaction was consistent with Djokovic’s post-match approach: he did not want his physical problems to take away from Navone’s victory.
The Bigger Picture for the 2026 US Open
Djokovic’s early elimination changes the landscape of the men’s draw.
The Serbian was one of the biggest names in the tournament and had been pursuing his fifth US Open championship and 25th Grand Slam title.
His exit opens additional opportunities for the remaining players in the draw.
Carlos Alcaraz entered the tournament as the defending champion after missing several months because of a right wrist injury, while Alexander Zverev was the top seed.
With Djokovic no longer in contention, attention will inevitably shift toward the other leading contenders and the battle for the final Grand Slam title of the 2026 season.